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Clinically meaningful weight loss, defined as a reduction of 5% in baseline BW, was achieved by 73.2%92.4% of semaglutide-treated participants, compared with 21.4%50.0% in the placebo arms [13, 38,39,40,41,42,43,44,45,46]

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Both hormones are released from intestinal enteroendocrine cells in response to nutrient intake, but their mechanisms of action differ in important ways

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However, the authors stress that caution remains appropriate for a small, specific group

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