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2015 Jul;4:212283
Although semaglutide and tirzepatide are GLP-1 agonists, tirzepatide generally works better for weight loss and obesity
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The purpose of this review is to further elucidate the mechanism of action of GLP-1RAs in helping individuals with overweight or obesity to achieve and maintain weight loss
Together, these changes may reduce the metabolic strain that can interfere with healthy insulin function and blood sugar regulation
Moreover, increasing focus on pediatric and elderly populations is vital, as T2DM prevalence rises in these groups
2019;257:S0165-327(19)30593-2
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